Clinical Study Data

Private Anonymous
Private & Anonymous

Declinol comes in discrete packaging. There is no group meetings. Take at home or at work in a matter of seconds.

Customize
Customize & Succeed

Choose a Declinol kit that fits both your budget and habit. Get to your desired results then maintain with ongoing wellness.

All Natural
All Natural & Non-addictive

Use Declinol as a tool to help overcome physical cravings for alcohol. Cut Back or quit, the choice is yours.

Support Services
Support Services

When you need to speak with someone, we are here for you. Also get a Free Consultation with a Joint Commission Certified counselor.

Private Anonymous
Private & Anonymous

Declinol comes in discrete packaging. There is no group meetings. Take at home or at work in a matter of seconds.

Customize
Customize & Succeed

Choose a Declinol kit that fits both your budget and habit. Get to your desired results then maintain with ongoing wellness.

All Natural
All Natural & Non-addictive

Use Declinol as a tool to help overcome physical cravings for alcohol. Cut Back or quit, the choice is yours.

Support Services
Support Services

When you need to speak with someone, we are here for you. Also get a Free Consultation with a Joint Commission Certified counselor.

Clinically Study Data


Clinical Studies

It is Declinol’s policy to study and test its products under independent clinical conditions. The studies focus not only on important numerical data, but also on the practical aspects of the addiction and withdrawal as the Client experiences it. In other words, numerical improvements aside, does the Client feel better? Do they think they made good progress? If they don’t, then positive-looking clinical test data will not matter to a Client, their support team, family, or friends. Client feedback is collected (whether positive or negative) and Client Testimonials are encouraged during and after the product program so we may further understand the product’s effectiveness- or areas that may be opportunities for improvement. Testing protocols are continuously expanded and improved, and the Practitioners and Client input is invaluable in data gathering and the quest to help those seeking to conquer difficult addictions

Declinol Study

Individuals addicted to alcohol often have extreme difficulty overcoming their addiction by will power alone. Even if they can quit, relapse is a strong possibility. However, if cravings along with typical withdrawal symptoms can be greatly reduced, it would be far easier to avoid alcohol consumption and more easily control cravings/urgings. A natural compound that could help reduce cravings can be instrumental in helping people eliminate the need to ingest alcohol, tapering over safe periods of time. As amount of alcohol is decreased, withdrawal is minimized and the body’s physiology is allowed to rebalance itself naturally.

Daidzin *2-7

For Declinol, a 60 day open label pilot study was conducted on 10 subjects who were all deemed to have alcohol dependence as determined by the AUD Questionnaire. The Alcohol Use Disorder Identification Test (AUDIT) is a test developed by the World Health Organization (WHO). It is a concise survey used to determine if an individual can be considered to a hazardous drinker or alcohol dependent. This test was created to be applicable on a global basis and was in fact validated in a study utilizing patients from 6 different countries. The AUDIT questionnaire has been found to be very efficient and has shown a high sensitivity (83%) and specificity (90%) for identifying alcohol dependence. The AUDIT is included in the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) under the diagnostic code 305.00. The study was overseen by Dr. Zainab Contractor, a Board Certified Neurologist practicing in Ohio. An exit interview was also conducted at the end of study that looked at reduction in cravings; ability to cut back on quantity consumed, withdrawal symptom reduction, physical and psychological need for alcohol, sense of calm, sleep patterns, and overall sense of health.

Following the study, the subjects re-took the AUDIT questionnaire when filling out the exit interview. The average starting score for the AUD was 16.1, which is categorized as full alcohol dependence. The post study score average was 3.7, demonstrating no level of alcohol dependence or hazardous drinking. In addition, 90% of subjects cut back or quit drinking and also reduced or eliminated cravings. Seven out of 10 people both reduced or eliminated withdrawals and were less in need of alcohol either physically or psychologically. Half of the group experienced better sleep, while 9 of 10 respondents felt better overall. Interestingly, all subjects said they would recommend Declinol to anyone attempting to reduce or eliminate alcohol usage.


Journal of Addiction Research and Therapy

Peer Review

References:
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3. The isoflavone puerarin reduces alcohol intake in heavy drinkers: A pilot study.Penetar DM, Toto LH, Farmer SL, Lee DY, Ma Z, Liu Y, Lukas SE. Behavioral Psychopharmacology Research Laboratory, McLean Hospital, Belmont, MA 02478, United States; Department of Psychiatry, Harvard Medical School, Boston, MA 02115, United States.
4. The Potential of Herbs and their Derivatives in Treating Addiction
Meletis CD, Zabriskie N. Natural approaches to treating addiction. Altern Complement Ther. December 2008;14(6): 275-281.
5. Alcohol Clin Exp Res. 1996 Apr;20(2):221-7.Suppression of alcohol intake after administration of the Chinese herbal medicine, NPI-028, and its derivatives.Overstreet DH, Lee YW, Rezvani AH, Pei YH, Criswell HE, Janowsky DS. Skipper Bowles Center for Alcohol Studies, University of North Carolina School of Medicine, Chapel Hill 27599-7178, USA
6. Carlson AJ, Torchiani B, Hallock R. Contributions to the physiology of the stomach. XXI: The supposed actions of the bitter tonic on the secretion of gastric juice in man and dog. JAMA, 1915;64(1):15-17.
7. Meyerhof W. Elucidation of mammalian bitter taste. Rev Physiol Biochem Pharmacol, 2005;154:37-72.
8. Behrens M, Meyerhof W. Gustatory and extragustatory functions of mammalian taste receptors. Physiol Behav, 2011;105(1): 4-13.
9. Valussi M. Functional foods with digestion-enhancing properties. Int J Food Sci Nutr, 2011[Epub ahead of print]
10. Finger TE, Kinnamon SC. Taste isn’t just for taste buds anymore. F1000 Biol Rep, 2011;3:20.
11. Wolf S, Mack M. Experimental study of the action of bitters on the stomach of a fistulous human subject. Drug Standards, 1956;24(3):98-101.
12. Mills SM, Bone K. Principles and Practice of Phytotherapy. Modern Herbal Medicine. Churchill Livingstone, Edinburgh, 2000:38-41.
13. Gebhardt R. Stimulation of acid secretion by extracts of Gentiana luteaL. in cultured cells from rat gastric mucosa. Pharm Pharmacol Lett, 1997;7(2-3):106-108.
14. Wegener T. Anwendung eines Trockenextraktes aus Gentiana lutea radix bei dyspeptischem Symptomenkomplex. ZPhytother, 1998;19:163-164.
15. http://www.ncbi.nlm.nih.gov/pmc/art/PMC13/
16. http://www.ncbi.nlm.nih.gov/pmc/art/PMC3/
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19. http://www.ncbi.nlm.nih.gov/pmc/art/P743/
20. http://www.lifescience.com/Amino.aspx
21. www.ncbi.nlm.nih.gov/pubmed/dopt=Abstract
22. http://www.drugs.com/npp/bupleurum.html
23. http://apps.who.int/medicinedocs/en/d/Js220
24. http://www.ncbi.nlm.nih.gov/pubmed/16265986?dopt=Abstract
25. http://www.itmonline.org/arts/rehmann.htm
26. http://www.ncbi.nlm.nih.gov/pubmed/23034094
27. Yukmijihwang-tang derivatives enhance cognitive processing in normal young adults: a double-blinded, placebo-controlled trial. Park E, Kang M, Oh JW, Jung M, Park C, Cho C, Kim C, Ji S, Lee Y, Choi H, Kim H, Ko S, Shin M, Park S, Kim HT, Hong M, Bae H. Department of Psychology, Korea University, Seoul, Korea.
28. http://www.ncbi.nlm.nih.gov/articles/P7913/
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pmc/articles/PMC1380207/

30. http://www.ncbi.nlm.nih.gov/pmc/art/P43/
31. Mayer, J, -Functional Foods for Health Program, USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA
32. http://www.ncbi.nlm.nih.gov/pubmed/19757811
33. Keller, B.C., Liposomes in Nutrition, Trends in Food Science & Technology 12 (2001) 25–31
34. Yoko Shojia,b, and Hideki Nakashimaa, Nutraceutics and Delivery Systems, Journal of Drug Targeting, 12(6):385-391, 2004
35. http://www.biopharmasci.com/nano.pdf
36. Torchilin VP. (2006)Adv Drug Deliv Rev. 2006 Dec 1;58(14):1532-55
Keller, B, PhD, Liposomes, Power Point http://www.biopharmasci.com/doc/nanosorb.ppt

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